Title: Genetics
1Genetics
- Genetics science of hereditary, how traits are
passed from one generation to the next - Inherited examples include Cystic fibrosis, skin
eye color, sickle cell disease
2Gregor Mendel
- Father of Genetics - (1860s) discovered that
the fundamental principles of genetics by
breeding pea plants
3I. Mendels Principles.. discovered
that inheritance follows rules of chance
- A. Law of Dominance
- The allele of a pair that is
- expressed is called dominant
- (strongest) while the allele that
- is not expressed (hidden) when
- present with another is called
- recessive.
- B. Law of Segregation and Recombination genetic
recombination - When the male gamete unites with the female
gamete to form a zygote, alleles recombine and
new combinations are formed. -
4 C. Crossing Over bringing about variation!
- when the chromosomes come together in the
beginning of meiosis, the arms of the chromosomes
may twist around each other, break, and rejoin
other chromosomes, thus creating linked genes and
increasing the genetic possibilities of the
offspring.
5D. Terms to know
- Homozygous- contains 2 identical alleles for the
same trait, (pure gene) - Heterozygous- contains 2 different alleles for
the same trait, (hybrid)
- Allele
- Alternate forms or versions of a gene.
- Slightly different DNA codes and occur at the
same location on homologous chromosomes
6Dominant allele
- The version of the gene that is expressed
(observed) when both alleles are present. - Symbolized with a capital letter Ex A
7Recessive allele
- The version of the gene that is not expressed
(not observed) when both alleles are present. - Symbolized with a lower case letter Ex a
8D. Terms to know
- Phenotype- physical characteristics are
observable - Genotype- Genetic combinations
- Example
- 1. tall pea plant TT tall (homozygous
dominant) - 2. dwarf pea plant tt dwarf (homozygous
recessive) - 3. tall pea plant Tt tall (heterozygous)
9E. Punnett square
- A Punnett square is used to show the possible
combinations of gametes
10Mendels Pea plants
Genotype -vs- Phenotype TT
tall pea plant (homozygous dominant) Tt
tall pea plant (heterozygous dominant)
tt dwarf pea plant (homozygous
recessive)
11Practice Mendels Pea Plants tall (TT)
vs. dwarf (tt) pea plants
12F. The Gene Chromosome Model
- Hereditary information is contained in genes,
which are composed of DNA, located in the
chromosomes of each cell. - Chromosomes are found in the nucleus of each cell.
13G. Gene Chromosome Theory
- Genes exist at definite locations in linear
sequence on a chromosome and are found in
homologous pairs. - Chromosome? GENES ? DNA ? alleles? traits
14- Accounts for the hereditary differences Mendel
observed. - Genes are segments of DNA that contain
instructions to make proteins. - Each gene carries a separate piece of
information. An inherited trait of an individual
can be determined by one gene, but is usually
determined by the interactions of many different
genes
15Regents Practice Question. Which chromosome pair
below best illustrates the gene-chromosome theory?
4 - You Are Correct!The gene-chromosome theory
states that genes are segments of DNA located on
chromosomes and are found in homologous pairs.
16Bellwork turn to your table partner and discuss
the questions below..
- 1. What organelle is known as the control
center of the cell? - 2. What structures are found in the nucleus?
- 3. What are located on chromosomes?
- 4. What are genes composed of?
17DNA The Intro Clip
All ABOUT DNA
18I. DNA Structure
- A. Building Blocks
- 1. Nucleic Acids! (NUCLEOTIDES)
- 2. also known as subunits
- B. Nucleic acids- (4 of them)
19C. DNA Shape
- 1. Each nucleic (acid) is made of 3 parts
- a. Sugar (Deoxyribose)
- b. Phosphate
- c. 1 of 4 Nitrogenous Bases
- A adenine
- T thymine
- C cytosine
- G guanine
20C. DNA Shape
- DNA IS DOUBLE STRANDED
- STRANDS TWIST TO FORM DOUBLE- HELIX
- NITROGEN BASES BIND TOGETHER TO MAKE TWO STRANDS
- A always binds with T
- G always binds with C
- All Teachers
- Go Crazy
- THIS IS CALLED THE
- BASE-PAIR RULE!
21Base Pair Ruling
22DNA Structure
G
G
T
A
C
G
C
C
T
-----C
-----C
-----A
-----T
-----G
-----C
-----G
-----G
-----A
- Lets Practice!
- One strand of DNA has the sequence you see.
- What is the complimentary strands sequence???
23Replication The Video Clip (102)
- http//www.youtube.com/watch?vz685FFqmrpo
24II. DNA Replication (copying)
CLICK HERE FOR DEMO
- A. When does DNA need to be copied????
- 1. During any cell division! (mitosis and
meiosis) - B. First, two strands are unzipped
- C. Second, enzymes bring new subunits to these
strands (templates) - D. Third, you end up with 2 identical double
helices - E. DNA acts as a PATTERN or TEMPLATE to make
copies of itself! - CLICK HERE FOR DEMO 2
25DNA Replication Diagram
Parent Strands
New complimentary strands
Free Floating Nucleotides
26Replication Practice- Step 1 Unzip
G
G
T
A
C
G
C
C
T
-----C
-----C
-----A
-----T
-----G
-----C
-----G
-----G
-----A
G
G
T
A
C
G
C
C
T
C
C
A
T
G
C
G
G
A
Enzymes UNZIP
27Replication Practice- Step 2 Add Subunits using
Base-Pair Rule
G
G
T
A
C
G
C
C
T
C
C
A
T
G
C
G
G
A
----C
----C
----A
----T
----G
----C
----G
----G
----A
G----
G----
T----
A----
C----
G----
C----
C----
T----
28THE DNA RAP!!!!
- http//www.youtube.com/watch?vd1UPf7lXeO8