ASSALAMU’ALAIKUM WR.WB.

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ASSALAMUALAIKUM WR.WB.
Tiada sia-sia Meraih Ilmu dan Mengamalkannya
Tambahkanlah Ilmuku dan Berilah aku pengertian
dengan baik
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DIURETIK
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• DASAR PENGGUNAAN
• PENINGKATAN TEKANAN INTRA OKULER /
  GLAUKOMA
• HIPOPROTEINEMIA
• HEART FAILLUR
• TRAUMATIC
• RENAL FAILLUR
• TOXIN EXCRETION
• DRUG OVER DOSE
• HYPERTENSI
• OEDEMA PULMONUM
• CALCIURIA

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Mechanism of action Inhibits Na Cl-
reabsorption in the loop of Henle proximal
distal tubules of nephron markedly increases
excretion of Cl-, Na, water also increases
excretion of K, Mg, Ca, ammonium, H,
bicarbonate, phosphate Side Effects/Adverse
Effects Dose-related hypokalemia,
dehydration, postural hypotension,
hypochloremic alkalosis, azotemia
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Mechanism of action Interferes with
reabsorption of Na Cl- in the distal
convoluted tubule of the nephron, thus
increases Na excretion, causing increased
urine output also increases excretion of K,
Mg, Ca, ammonium, H, bicarbonate,
phosphate decreases calcium uric acid
excretion Side Effects Frequent -
hypokalemia, dizziness, muscle weakness, dry
mouth, thirst, Interactions the same as Lasix,
due to effects on lytes