Delve1Insight

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SICKLE CELL DISEASE
Market Insights, Epidemiology and Market
Forecast-2028
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Sickle Cell Disease
Sickle Cell Disease, also known as sickle cell
anemia, includes group of disorders affecting the
red blood cells in the body.
It is an inherited blood disorder characterized
by defective hemoglobin. In this disease, there
aren't enough healthy red blood cells to carry
adequate oxygen throughout the body.
Sickle cell disease is irreversible that affects
males and females equally, and is responsible for
increased morbidity and mortality in affected
persons.

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Sickle Cell Disease Epidemiology
Among the EU5 countries, France has the highest
prevalent population with 15,000 cases followed
by the United Kingdom, which has a prevalent
population of 13,000 in 2017.
There is no Sickle Cell Disease prevalence in
Japan since the disease doesnt occur in the
Japanese population
There were approximately 133,385 Sickle Cell
Disease prevalent cases in 2017 in the 6MM.
The United States accounts for the highest Sickle
Cell Disease prevalent population followed by the
EU5 countries.

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Sickle Cell Disease Market
Most of Sickle Cell Disease treatments are
dominated by off label and off patent medications
(HU Iron Chelators, Analgesics, Antibiotics,
vaccines), to address the complications or for
specific Sickle Cell Disease symptoms.
Hydroxyurea was the first ever drug approved for
Sickle Cell Disease treatment in 1998. The most
distressing issue with Hydroxyurea was the lack
of FDA approval for infants with Sickle Cell
Disease in the United States.  
Sickle Cell Disease market size was majorly
dependent on the use of Hydroxyurea till 2017,
when Endari was launched.
The approval of the Emmauss Endari for treating
Sickle Cell Disease complications in the United
States in 2017 had marked a significant
advancement in Sickle Cell Disease treatment.
Companies are working on novel mechanisms of
action (Pan-Selection Inhibitor) will further
fuel the Sickle Cell Disease market growth.

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Sickle Cell Disease Emerging Drugs and
Companies
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Company- GBT Therapeutics Drug- Voxelotor/ GBT-440
Company- Pfizer Drug- Rivipansel
Company- Novartis Drug- Crizanlizumab
Company- Imara Therapeutics Drug- IMR-687

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Complete Information
For complete information on Sickle
Cell Disease Market Insight, Epidemiology and
Market Forecast - 2028 please click the link
below
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DelveInsight is a premier Business Consulting and
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life science segment. With a wide array of smart
end-to-end solutions, the firm helps the global
Pharmaceutical and Bio-Tech companies formulate
prudent business decisions for improving their
performances to stay ahead of the competitors.
To provide insights across the value chain and
helping the organization to take a prudent
business decision through the use and analysis of
actionable market intelligence. The mission also
is to provide the most effective result and
efficient service with utmost client care for
maintaining a long-term relationship with them.
To be the most trusted market research business
consulting firm in the world and to continue
enable the Pharma Bio-Tech companies to achieve
their goals with the best strategic insight and
competitive solution. The vision also is
inclusive of becoming a one-stop solution
provider for the entire gamut of drug development
process.

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