Conclusions

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Conclusions

• George Siber, M.D.C.M.

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Efficacy Against Otitis Media

FinOM () NCKP () Vaccine Serotype OM 57
(44, 67) 69 (0.4, 93) Vaccine Related
Serotype OM 51 (27, 67) Non Vaccine Serotype
OM -33 (-80, 1) All Pnc OM
34 (21, 45) Recurrent OM 16
(-6, 35) 12 (7, 16) All OM
6 (-4, 16) 7 (4, 9) Tube
Placement 441 (19, 62) 24 (12,
35)
Ruptured ear drum due to vaccine types

1 FinOM follow up
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Public Health Impact of Prevnar on Otitis Media

• 1.2 to 1.4 million office visits prevented a year
  
• Associated decrease in antibiotic use
• Prevention of 60,000 ear tube surgeries a year

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Otitis Media Indication

• Supported by two randomized controlled trials
  showing statistically significant decreases in OM
  outcomes
• Prevnar immunization has an important medical
  effect on otitis media disease and its
  consequences
• Addition to label ensures accurate communication
  of information to physicians and parents
• Vaccines against individual otitis pathogens are
  all likely to have low overall impact on OM

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Thank you