Lawrence N' Tanenbaum, M'D' FACR

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3T HDMRI in Clinical Practice

• Lawrence N. Tanenbaum, M.D. FACR
• NJ Neuroscience Institute - Seton Hall University
  
• Edison Imaging- JFK Medical Center
• www.drtmasters.com drt_at_drtmasters.com
• Edison, New Jersey

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3T Challenges

• surface coil availability
• SAR limitations
• susceptibility artifact
• T1 contrast

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3T HDMRI

• new generation magnet designs
• more SAR efficient
• short bore, 60 cm diameter
• superb homogeneity, off isocenter performance
• wide range of HD surface coils
• EXCITE HD backbone
• RF
• reconstruction
• post processing

ssFSE
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HD surface coils
quadrature
8 channel
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1.5 T quad
3T 8 channel
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1.5T 8 channel
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3T 8 channel
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1.5 T Excite
3 T Excite
8 channel
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1.5 T Excite
3 T Excite
8 channel
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pFSE
multiple sclerosis
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Giant cell astrocytoma 3T
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0.025 mmol/kg
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320 x 224 30 slices 4 mm 8 ch head
2 nex 213
ASSET 45 sec
1 nex 74 sec
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45 sec ASSET
320 x 224, 30 slices, 4 mm, 8 ch head
1 nex 74 sec
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53 sec
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phase-sensitive inversion-recovery
3 mm
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3D SPGR 1.2 mm
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3D magnetization tranfser SPGR
metastatic disease
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3D FLAIR
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PROPELLER FSE Periodically Rotated Overlapping
ParallEL lines with Enhanced Reconstruction
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Propellerradial k-space trajectory

• each TR, all phase-encoded lines for a blade
  are collected during one ET
• the blades are successively rotated in k-space
  by an incremental angle
• hub of each blade in center of k-space
  oversampling region rich in SNR

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Propellermodified radial k-space trajectory

• k-space center oversampling
• inherently motion resistant
• allows correction of data for rotation and
  translation motion

FSE
propeller
Forbes K, Pipe J, Bird CR, Heiserman J
Propeller MRI Clinical testing of a novel
technique for quantification and compensation of
head motion. JMRI 2001
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Propellermotion corrections
Signal Acquisition

• blade sub-images generated
• motion effects detectable in data
• data corrected for rotation and translation
  motion
• bad bulk through-plane data rejected

Phase Correction
Rotation Correction
Translation Correction
Correlation weighting
Final Reconstruction
Forbes K, Pipe J, Bird CR, Heiserman J
Propeller MRI Clinical testing of a novel
technique for quantification and compensation of
head motion. JMRI 2001
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Propellermotion corrections
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Propellerregistration and rejection
time
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Propeller
FSE
1.5T
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Propellerimpact in clinical practice

• routine imaging without motion artifact
• high resolution imaging without ghosting
• improved SNR over rectilinear encoding
• DWI without artifact

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8 channel coil
480 x 416 FSE
480 diam Propeller
1.5T
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3 months old unsedated
Conventional FLAIR
Propeller FSE
Propeller FLAIR
1.5T
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Propeller FLAIR
Conventional FLAIR
1.5T
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Propeller FSE
Propeller FLAIR
1.5T
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3T FLAIR
rectilinear
propeller
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3T FLAIR
rectilinear
propeller
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3T brain
propeller
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Superiority of Propeller FSE to conventional FSE
for 8 channel brain imaging in clinical practice

• LN Tanenbaum MD1, J Pipe PhD2, A Gaddapati PhD3,
  M Hartley3, J Debbins PhD3, N Eshkar MD1
• NJ Neuroscience Institute / Edison Imaging1
• Barrow Neurological Institute2
• GE Medical Systems3

ASNR 2002
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Superiority of Propeller FSE FLAIR to
conventional FSE FLAIR for 8 channel brain
imaging in clinical practice

• LN Tanenbaum MD1, J Pipe PhD2, A Gaddapati PhD3,
  M Hartley3, J Debbins PhD3, N Eshkar MD1
• NJ Neuroscience Institute / Edison Imaging1
• Barrow Neurological Institute2
• GE Medical Systems3

ASNR 2003
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CONCLUSION

• Propeller T2 and FLAIR techniques are superior to
  conventional techniques offering superior SNR as
  well as resistance to motion artifacts and
  ghosting.
• Propeller T2 and FLAIR can replace conventional
  FSE acquisitions for routine T2-weighted imaging
  in the clinical setting.

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3T Propeller
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3T pFSE
AC polyp
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3T Propeller
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HD MRI .37 mm in plane
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HD MRI 3T
.35 mm in plane
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1024 x 384 3 mm
High def MRI .23 x .63 mm in plane
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3D FIESTA 3T 8 channel HD 1 mm
AICA loop
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vestibular schwannoma
3D FIESTA 512 x256 1mm
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3T DWI
multiple sclerosis
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no ASSET
8 channel head coil 1.5 T
ASSET
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reduced susceptibility artifact
ASSET
no ASSET
1200 B - 3 Tesla 8 ch
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3T Diffusion imaging
Propeller FSE
ssEPI
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3T Diffusion imaging
Propeller FSE
ssEPI
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3 mm diffusion tensor imaging
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Jellison, et.al. AJNR 25356-369, March 2004
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anterior limb int capsule
posterior limb int capsule
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cortico spinal fibers
sup long fasciculus
inf long fasciculus
post limb int cap
cortico spinal fibers
post limb int cap
post limb int cap
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Hippocampal sclerosis
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Hippocampal sclerosis
3 mm 55 dirns 5 min
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Brainwave FMRI
isotropic anatomic background study
auto-segmentation
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motor and language
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Integrated fMRI
motor
language
tumor
Preop assessment metastasis resection
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motor
language
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Cho
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.35 x .80 x 1.0 mm resolution
multislab 3D TOF 512 x 224 414
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ASSET TOF 3T Excite
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.35 x .80 mm resolution
multislab 3D TOF 512 x 224 1mm 414
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1.7 mm aneurysm
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ophthalmic artery 3.5 mm aneurysm
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3 wks s/p worst headache ever
right CN III Palsy pupil involved
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CA
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Post GDC coiling suprasellar ICA aneurysm
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1024 TOF
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WG Bradley MD
1024 x 608 16 FOV .8 x .4 mm
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HD 1024 MRA
.19 x .52 mm in plane res
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fast MRA ASSET x 2 149
512 x 128 20 FOV 1 mm /0.5 mm 32 pps / overlap 3
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3D TOF
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48 FOV 8 channel torso array
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48 FOV Left SCA stenosis
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ASSET TRICKS 8 x acceleration 2.0 second temporal
resolution 48 FOV
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Contrast MRA .1 mmol/kg 8 channel coil
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0.1 mmol/kg 2mm / 1 mm elliptic centric -
partial Kz 27 sec 352 x 224 35 FOV
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Renal a. stenosis 3T 8 channel
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head coil z-axis homogeneity
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suspected fistula
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TRICKS 3T c-c fistula
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TRICKS 3T c-c fistula
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Propeller FSE
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1.5T
3.0T
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1.5T
3.0T
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3.0T
1.5T
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3.0T
1.5T
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3.0T
1.5T
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3.0
1.5
3.0
1.5
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3.0
1.5
3.0
1.5
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RF fat suppresssion
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diskitis osteomyelitis
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40 FOV 8 ch spine
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2.0 mm
2.5 mm
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3T
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2.5 mm 230
2 mm
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2 mm / 1 mm
3D MERGE 3T
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2 mm / 1 mm
3D MERGE 3T
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3T MERGE
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neurofibroma 3T
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post gamma knife radiation myelopathy
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1.5T pre
3.0T post
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New York City Times Square June 24th 26th
2005
ESI Educational Symposia Clinical 3.0T Imaging
Symposium Clinical speakers 3.0T whole-body
topics Application in clinical practice
L. Tanenbaum, M.D. FACR M. Shapiro, M.D. T.
Grist, M.D.
L. Turnbull, M.D. K. Thulborn, M.D. J. Weinreb,
M.D. R. Ramnuth, M.D.
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