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YSR 12, (14, 16) Motor development 2, 5. School achievement 5, 12, (14, 16) Family ... Workshop On Methodology of Twin And Family Studies. Boulder, CO, 2004 ... – PowerPoint PPT presentation

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Title: Dia%201


1
Netherlands Twin Register (NTR)
30,000 twin pairs registered at birth, born after
1986
Questionnaire variables Zygosity, health and
growth 2, 3, 5, 7, 10, 12, (14, 16) SES
3, 7, 10, 12 Problem behavior
CBCL (Devereux at 5) 3, 5, 7, 10,
12 TRF 7, 10, 12 YSR
12, (14, 16) Motor development 2,
5 School achievement 5,
12, (14, 16) Family Composition
5, 12, (14, 16)
2
Aggressive and Rule-Breaking Behavior
3
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Aggressive Behavior 10 year old twins rated by
their mother
skewness 1.346
4
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Square root transformed Aggressive Behavior 10
year old twins rated by their mother
skewness .046
5
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
SPSS descriptives
Pairs Ma Mb Vara Varb r MZM 514 2.41 2.38 1.62
1.56 .84 DZM 467 2.24 2.31 1.62 1.50 .50 MZF
609 1.98 1.90 1.31 1.28 .79 DZF 452 1.95 1.91 1.
36 1.26 .54 DOSm-f 885 2.23 1.81 1.57 1.29 .47
6
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Mx Means and Variance (Saturated)
Males -2LL df par ??2 df p AIC means
free 5712.15 1956 10 eq means 5716.90
1959 7 4.755 3 .191 -1.245 eq m/ eq v 5718.77
1962 4 6.622 6 .357 -5.378
Females -2LL df par ??2 df p AIC means
free 5844.97 2120 10 eq means 5854.08
2123 7 9.110 3 .028 3.11 eq m/ eq v 5855.33
2126 4 10.360 6 0.110 -1.64 eq v 5846.23
2123 7 1.257 3 0.139 -4.74
7
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Mx Estimates of Means and Variances
T1 T2 VT1 VT2 r r (eq m) MZF 1.99 1.90 1.31 1.2
8 .792 .789 DZF 1.95 1.91 1.36 1.26 .538 .537 MZ
M 2.41 2.38 1.61 1.56 .83 .838 DZM 2.24 2.30 1.6
1 1.49 .50 .499
8
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Practical Test Means and Variance in 4 group
script
F\ meike\ uni example \ satm.mx
  • Create a 4 group script with males and females
  • test means and variances

9
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Mx Means 4 groups
Males/Females -2LL df ?2 df p AIC eqmm
eqmf 11574.103 4088 mm mf 11639.178 4089
65.075 1 .00 63.075 eqvar 11586.696 4089
12.591 1 .00 10.593
10
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Model Fitting Results
Boys -2LL df ?2 df p AIC ACE 5718.768 1962 AE 57
24.465 1963 5.696 1 .017 3.696 CE 5869.551 1962 15
0.78 1 .00 148.783 A .67 C.17 E.16
Girls -2LL df ?2 ?df p AIC ACE 5855.335 2126 AE
5870.988 2127 15.65 1 .00 13.65 CE 5942.60 2127 87
.26 1 .00 85.265 A .52 C.28 E.20
11
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Mx Practical ACE model for 4 groups F\meike\uni
example\unim.mx Create a 4 group script with
males and females Estimate A, C. and E
12
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
4 group analysis
-2LL df ?2 df p
AIC ACE 11574.103 4088 ACEnsd 11591.813 4091 1771
3 3 .001 11.710 Boys 5718.768 1962 Girls
5855.335 2126
Am Af Cm Cf Em Ef ACE .67 .52 .17 .28 .16 .20
(.54-.81) (.40-.65) (.03-.29)
(.15-.39) (.14-.19) (.18-.23) ACEnsd .60
.22 .18 (.51-.69) (.12-.30) (.17-.20)
13
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
Mx Means SS and OS twins (5 groups)
Males -2LL df ?2 df p AIC ss ? os
17011.614 5851 ss os
17015.035 5852 3.42 1 .06 1.421 Mean SS
2.33 Mean OS 2.23 Females -2LL
df ?2 df p AIC ss ? os 17011.614 5851 ss
os 17042.096 5852 30.48 1 .00 28.482 Mea
n SS 1.94 Mean OS 1.81
14
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
The Opposite sex group
Open unimfh_5groups
15
Table 1 CBCL-items of the syndrome Aggressive
Behavior for the CBCL/2-3 and CBCL/4-18
5 group analysis
-2LL df ?2 df p
AIC Hfree 14229.726 4986 Hfixed
.5 14229.726 4987 0 1
-2.00 ACEnsd 14246.423 4990 16.696 4
.002 8.696
Estimate H.5 (.42-.50)
16
Estimates of variance components
2groups 4 groups 5 groups Am .67 .67
(.54-.81) .63 (.53-.72) Af .52 .52
(.40-.65) .50 (.39-.62) Cm .17 .17
(.03-.29) .20 (.11- .30) Cf .28 .28
(.15-.39) .29 (.18-.40) Em .16 .16
(.14-.19) .17 (.15-.19) Ef .21 .20
(.18-.23) .21 (.18-.23)
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