Aminosyrer

1

• Aminosyrer
• Peter Højrup
• php_at_bmb.sdu.dk
• www.protein.sdu.dk

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General formula and zwitterion
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Formation of a peptide bond
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Aliphatic residues
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Aromatic residues
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Hydroxyl and sulfur containing residues
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Basic residues
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Acidic and amide residues
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Chemical properties of the amino acid residues
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Chemical properties of the amino acid residues
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Formation of a disulfide bond
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Titration of an amino acid
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Isoelectric point
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Polypeptide
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Scheme for identifying atoms
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Optical activity - Enantiomers
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Polarimeter
Observeret rotation (grader)
?D25
Optisk vej x koncentration (g cm-3)
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Fischer convention for stereo-isomers
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L-configuration
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CORN mnemonic
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Fischer projections of the four stereoisomers
Enantiomerer
Diastereomerer
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Stereoisomers of cystine
To identiske asymmetriske centre
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Cahn-Ingold-Prelog system
SHgtOHgtNH2gtCOOHgtCHOgtCH2OHgtC6H5gtCH3gt2Hgt1H
Atomer med højere atom nummer bundet til et
chiralt center rangerer over atomer af lavere
atom nummer.
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(RS)-system representation
Hvis W?X ?Y er med uret er det asymmetriske
center i (R) konfiguration
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Newman projection
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Pro chiralt center - Ethanol
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Acetaldehyde
re siden
si siden
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Modified amino acids included in proteins
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Modified amino acids non protein compounds