???(vitamin)????????????,??????????????,??????????????????? - PowerPoint PPT Presentation

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???(vitamin)????????????,??????????????,???????????????????

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Title: 1 Author: huangxin Last modified by: rose Created Date: 6/1/2003 6:59:45 AM Document presentation format: Company – PowerPoint PPT presentation

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Title: ???(vitamin)????????????,??????????????,???????????????????


1
??? ??????
???
2
??? ?????
????
  • ???(vitamin)????????????,??????????????,?????????
    ??????????
  • ???????,?????????????????????????,????????,???????
  • ?????????????????(?????)?

3
?? ??
???????
  • ?????A?B?C?D???,????????????????????,??????????
    ????????
  • ?????????????,?

1967?1970?????????????????????????V???????,???????
???
4
????
????????,????????,?????????????????(lipid-solub
le vitamins)???????(water-soluble vitamins)????
5
??? ??????
????????B????????C??????????????????????,??????
???,??????????????????????,?????????????
6
 ?????Bl (???)
(?)????????????????
7
(?)????-??????(TPP)
???ATP ? TPPAMP
8
(?)????
? B1?????TPP,????????a-? ?????????,??a-?????
? ????????????,??????
CH3COCOOH?CH3CHOCO2
? ???????????
? ??????
9
(?)???Bl???
  • ?TPP???????,?VB1,TPP????,??????????a-???????????,?
    ????,????????????????????????????
  • VB1??????????,?????B1?,??????????,????????,???????
    ??,???????????????????????????????

10
 ?????B2
  • ???B2?????(riboflavin),??????????????????

11
(?)???B2??
???
????
12
???B2??????FMN?FAD
FAD?????????
FMN??????
13
(?)????????
????FMN?FAD??????????????
14
  • ???B2???,???????????????????
  • ????????1.21.5mg,????????????????????????B2????

15
????
(?)??
???????????B3?
16
??ACoA?ACP(??????)???????????
17
(?)????
???C0A?ACP??????????,??????????????,?? 70????
C0A? ACP?
18
 ?????B5
(?)?????
???B5?????PP????(?)?????,?????(nicotinic
acid)?????(nicotinamide),?????????
??? ????
19
  • ???PP????????,?????????????PP,??????,?1/60,?60mg?
    ??????? lmg??????????????,????????PP?????????

20
???PP????????
NAD NADP
?????????? ????????????
21
  •   NAD? NADP???????????????,?????????????????????
    ???

22
?????B6
(?)??
???B6?????????????,?????????????????????????????
,??????
23
(No Transcript)
24
(?)????????
  • ??????????????????????,???????????????????????
  • ?????????????,???-???????,?-?????????????????????
    ??B6???????????????
  • ????????B6????????????????????,?????????,????????
    ?,??????B6?

25
?????
???(biotin)??????B7????H,????????????????,??????
?????????,??????,????????????
(?)?????
26
(?)????????
  • ??????????????,????????,??CO2?????
  • ??????????????????????????????,??????????,???????
    ?????????????????,????????????

27
????
(?)?????
  • ??(folic acid)?????????????,???????????B11?

28
5.2 ??????-??
29
(?)????????
  •   FH4?????????????,???? N5? N10
    ?????????????????????????????,???????????????????,
    DNA????????,??????DNA????,????????,??????,????????
    ??

30
  • ???????????????,?????????,???????????

31
  • ???????????????????????????????????,???????????

32
?????B12
(?)??
???B12?????(coholamine),????????????????B12?????
??????,????????,????????????????5-???????,???????
?B12????,?????????????
33
??? 5-???????
34
(?)B12????????
  • ??
  • ?????????????????
  • ???
  • ?????????

35
?????
????????????a-??????????????????????,???????,??
????????? ?????????
36
?????C
(?)?????
  • ???C??????(ascorbic acid)???? C2?C3???????????????
    ???? H,?????,?????????, C2? C3???????????????????
    ??????

37
  • L-?????????????
  • ????????????????
  • ?????????C,???C?????????????,????????????????????
    ,????????????????C?????????????????????C,????????,
    ?????????C??????

38
(?)????????
1.?????????????????????????????????,?????,????????
?????????????
2.??????????40???????????C?????????7-a???????7-a-
???????
39
 3.???C???????????????????????,???????????????????
?,?????C???? C???,?????????????
4.????C???,?????????
40
5.???C??????????
  •  ???C??????????,???????-SH???????
  •  ???C?????????????(MHb)???????(Hb),??????????
  •  ???C??????A?E????,???????????????????????????????
    ?60mg?

41
??? ??????
?????A
(?)??
  • ???A????????????????A????? A1? A2 ?

42
  • Al?????,???A?????????????????,???????????
  • ?????????A,??ß-?????1??ß-????????2?????,?????ß-??
    ???????A??

43
?????A?????????????? ????????????????????????
44
?????D ?????D??????????? ????????,???
45
VD????????? ??????????
46
?????E(???) Evans 1922 ?? ?????E?????????????? ??
?????????
47
????(??????)
48
?????K(?????) ???????????????? ?????K???????????
??????????  
49
?????????????
  • ??? ??
    ??
  • 1. B1(???) TPP
    a -??????
  • 2. B2(??? ) FMN?FAD
    ???
  • 3. PP ???(??) NAD?NADP
    ???
  • 4. ??(???) CoA
    ????
  • 5. B6 ???(???) ?????(?) ????????
  • 6. ??
    FH4(THFA) ??????
  • 7. ???
    ????
  • 8. C(????)
    ??????
  • ???
    ????????
  • B12(????)
    ?????

  • ??????

50
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