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YEWHI-Study - A Comparison Between Blue Light
Filtering and Ultraviolet Light Filtering
Intraocular lenses B. Neumaier-Ammerer, S. Felke,
F. Zeiler, S. Hagen, P. Haas, S. Binder No
financial interest-all authors
Department of Ophthalmology Rudolf Foundation
Clinic Vienna Head Prof. Dr. Susanne Binder
The Ludwig Boltzmann Institute of Retinology and
Biomicroscopic Lasersurgery
Purpose To evaluate the difference between
yellow tinted and non-tinted intraocular lenses
(IOL) relative to contrast sensitivity, glare,
colour perception and visual acuity at different
light intensities. Study design Prospective
randomised study Method 80 eyes of 80 patients
were included. 20 IOLs of each of the following
lens types were implanted HOYA AF-1 UY (yellow),
HOYA AF-1 UV, Alcon Acrysof SN60AC (yellow),
Alcon Acrysof SA60AC. Parameters of interest
were reading acuity tested with Radner charts
Snellen BCVA (far distance) contrast
sensitivity tests with Pelli Robsen Charts and
CSV-1000E Vector Vision Test with and without
glare colour perception with Ishihara Charts and
the Roth 28 Hue Test All tests were performed
under standardized light conditions and different
light intensities ranging form 10 to 1000 lux.
Study follow ups 1 and 8 weeks after surgery
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Results I
measured in Snellen
log RAD

• There was no significant difference in far or
  near distance visual acuity at any light
  intensity (10,100, 1000 lux) between the yellow
  tinted and the clear IOLs .

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Results II - contrast sensitivity tests8 weeks
postop

• At the 8 weeks follow up there was no
  significant difference in the mean contrast
  sensitivity quotient (Pelli Robsen chart) between
  yellow and clear intraocular lenses at 10, 100
  and 100 lux.
• Even when tested with glare, the contrast-
  sensitivity-values at different spatial
  frequences (Vector-vision-1000-Test) were within
  the normal ranges in all four groups.

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Results III colour perception8 weeks postop

• Patients with blue light filtering IOLs made
  significant more mistakes in the blue light
  spectrum when tested under mesopic conditions at
  10 lux (p 0,0015).
• Under photopic conditions (1000 lux) there was
  no significant difference between yellow and
  clear IOLs (p0,8) in the blue light spectrum.

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Conclusion

• We could not find any difference between yellow
  (blue light filtering) and clear intraocular
  lenses, except colour perception in the blue
  light spectrum under mesopic conditions. How far
  this reduced blue perception is disturbing the
  patient is uncertain at the moment.
• In a quality of life questionnaire our patients
  did not quote any impairment, i.e. the
  postoperative patient satisfaction was not due to
  the implanted lens type.
• If the implantation of yellow tinted IOLs could
  prevent the development of macular degeneration
  this would compensate the reduced blue colour
  perception in mesopic light conditions. But this
  macular protection of yellow lenses has to be
  confirmed in long term studies.