Habituation, Sensitization and Classical Conditioning in Invertebrate Models

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10/4/2007 Habituation, Sensitization and
Classical Conditioning in Invertebrate
Models   Aplysia Californica   Habituation Circ
uitry Molecular Mechanism   Sensitization Ci
rcuitry Molecular Mechanism   Classical
Conditioning Circuitry Molecular
Mechanism Drosophila melanogaster Classical
Conditioning  
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Donald Hebb When an axon of cell A excites cell
B and repeatedly or persistently takes part in
firing it, some growth processes or metabolic
change takes place in one or both cells so that
As efficiency as one of the cells firing B is
increased. Paraphrase Synaptic connections are
strengthened when the presynaptic and the
postsynaptic neurons are active simultaneously.
Paraphrase II Neurons that fire together, wire
together
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Fig 63-1
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Circuitry Diagram
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Fig 63-1
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Fig 63-2
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Fig 63-1
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Short-term vs Long Term
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Fig 63-2
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Fig. 36-6
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Difference Between Habituation and Adaptation
Mechanism of Habituation? Distributed synaptic
plasticity.
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Sensitization
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Circuitry For Sensitization
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Fig 63-3
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Signal Transduction Pathway
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In-class Exercise1
What effects would you expect from activated PKA
in the sensory neuron? List them and explain
why they would increase the strength of the
synapse.
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Fig 63-3
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Kandel Fig 63-6
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Fig 63-5
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Classical Conditioning
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Kandel Fig. 36-7B
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Circuitry For Classical Conditioning
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Fig 63-4
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Fig 63-4
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Kandel Fig. 36-8
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Fig 63-5
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Drosophila Classical Conditioning
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Roman and Davis (2001)Bioessays 23571 Figure 1
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Roman and Davis (2001) Bioessays 23571 Figure 4
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Roman and Davis (2001) Bioessays 23571 Figure 4