Title: Humans
1Humans Ablation/lesion studies - first way to
study Imaging - structure - X-ray, CT,
MRI - function - PET, fMRI, EEG
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7Radio active L-DOPA in Basal Ganglia
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27Cooling the brain - affects activity
28RF lesion
29Electrical techniques Stimulation - see what
happens - motor - perceptual Recording -
intracellular - extracellular - multiple
units - invasive EEG
30Excitotoxic lesion - right damaged
31Activity (in dead animals) 2-deoxyglucose -
glucose - only energy - 2-DG - radioactive
variety - taken up, not metabolized - prepare
slices like x-ray - dark spots, high activity
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36Behavioral Techniques Neuropsychological Testing
- Humans Wechler Adult Intelligence Scale
(WAIS) - language (receptive vs production) -
language lateralization - memory - types -
frontal lobe function - Wisconsin Card Sorting
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41Species common behavior - open field test -
aggressive/defensive - intruder paradigm -
sexual behaviors - male vs female
42Conditioning Paradigms - animal learning -
classic - operant Semi-natural animal
learning paradigms - taste aversion - radial
arm maze - Morris maze (milk maze) - defensive
burying
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