Ergosterol PowerPoint PPT Presentations

Classification of antifungal drugs: Can be classify to six groups. 1- Antibiotics [ Amphotricin B,(AMB), Nystatin, Greiofulvin] 2- Antimetabolities [ 5- Flucytosine,(5-FC), inhibition nucleic acid synthesis] 3- Azoles: a-Imidazoles: Bifonazole, Clotrimazole, Econazole, Ketoconazole, Miconazol. b- Triazoles: Fluconazole, Itraconazole, Voriconazole Inhibition of ergosterol synthesis. 4- Allylamine [Terbinafine, Naftifine ] Inhibition of Lanosterol and Ergosterol synthesis. 5- Echinocandins Inhibit fungal cell wall biosynthesis 6- Miscellaneous Antifungals [Tolnaftant, Undecylenic acid, Benzoic acid, Ciclopirox olamine.]

Griseofulvin binds microtubule proteins, inhibit cell wall synthesis. Terbinafine is an ergosterol ... Are we going to hit MRSA like situation in mycology? ...

In fungi: ergosterol in membranes: higher affinity than. mammalian ... Impair synthesis of ergosterol; inhibit sterol 14 a-demethylase (of cyt. P450) ...

... storage compound glycogen mycolaminarins sterols ergosterol fucosterol Phyla: Chytridiomycota Oomycota (emphasized Zygomycota Myxomycota in class ...

Attaches to ergosterol disrupts cell membrane cell lysis ... Big pharmaceutical companies. Smaller ($) market for anti-infectives ...

It binds to fungal membrane sterols (ergosterol) and alters permeability ... can precipitate acute intermittent porphyria. possibly teratogenic ...

V TAM NLER V TAM N D (Antira itik Vitamin) Prekursorleri Ergosterol (vitamin D2 olarak bilinen ergokalsiferol n prekursoru bitki, maya ve mantarlarda ...

Therefore, agents that interact with fungal targets not found in eukaryotic ... The membranes become leaky. Ergosterol is not present in mammalian membranes. ...

Highly complex mixture of geological materials, dead organic matter, living ... Related by-products (including glomalin, ergosterol) and enzymes ...

Analysing transcriptome data: II the antioxidant response ... Ergosterol. Catalase. Eliminates cellular H2O2. H2O2 2H2O O2. Yeast possesses 2 catalase enzymes ...

First proposed in 1972 by Singer and Nicolson. Lipids: The ' ... Ergosterol. Sterols absent from some membranes. Hopanoids. Slide 14. Sterols (cont) Slide 15 ...

Muscle weakness, polyneuritis and beriberi. Vitamin ?3. Water-soluble. ... (ergosterol) under the influence of UV rays. Osteomalacia in adults, rachitis in children. ...

A new HPLC-DAD method for sterols analysis in biological fluids ... because it shows better results than other detectors. Validation of Method For ergosterol, ...

... of cytochrome P-450Impairment of Ergosterol synthesis in the fungal cell ... Peak plasma concentrations (C-max) occur between 1 and 2 hours with a terminal ...

DNA and Fatty acids are more suitable as biomarkers than RNA and Proteins. Why? ... Ergosterol for fungi. Photosynthetic pigments for photosynthetic bacteria, algae. ...

Ankara Turkey. MOST COMMON FUNGAL PATHOGENS. Dermatophytes. Candida. Aspergillus. Cryptococcus ... Triazoles: Fluconazole, itraconazole, voriconazole, ...

Selenium and tar extract shampoos ... http://dermnetnz.org/dermatitis/seborrhoeic-dermatitis.html ... Lysine biosynthesis (DAP/AAA) Fungal growth regulators ...

Trumac Healthcare is best PCD Pharma Manufacturer Company of medicines, capsules, injectable, syrups etc. Our team of talented and highly skilled professionals works dedicatedly for your good health.

Antijamur SRIDANA, S.Farm.,Apt Anti Jamur Infeksi yang disebabkan oleh jamur disebut mikosis. Infeksi jamur secara umum dibedakan menjadi infeksi jamur sistemik dan ...

STEROIDA STEROIDA SENYAWAAN YANG DENGAN INTI SIKLO PENTANO PERHIDRO PENANTREN SISTEM CINCIN A,B,C DAN D KOLESTAN menyatakan suatu gugus diproyeksikan ...

Caused by dimorphic fungi. * Dr. Emad AbdElhameed Morad General mycology* Systemic mycoses Affect immunocompromised individuals Examples are: ...

Antimicrobial Agents (General considerations) Prof. R. K. Dixit Pharmacology and Therapeutics K.G.M.U. Lucknow dixitkumarrakesh@gmail.com Objectives .

Title: PowerPoint Presentation Last modified by: H&M Created Date: 1/1/1601 12:00:00 AM Document presentation format: Presentaci n en pantalla Other titles

Antifungal agents Pawitra Pulbutr M.Sc. In Pharm (Pharmacology) ...

'the drug made me the sickest I have ever been-it was worse than the disease' ... Pharmaceutical Research, 2001-Sep;18(9):1305-9. ...

Other copper sulfate mixtures. Currently replaced with copper-based compounds ... Mercurous chloride. Heavy metal (Hg) compounds ...

Antijamur SRIDANA, S.Farm.,Apt Anti Jamur Infeksi yang disebabkan oleh jamur disebut mikosis. Infeksi jamur secara umum dibedakan menjadi infeksi jamur sistemik dan ...

Steroids, Aspergillus, and Antifungals Russell E. Lewis, Pharm.D., FCCP, BCPS Associate Professor University of Houston College of Pharmacy & The University of Texas ...

The lungs are the most common portal of entry of pathogenic ... Aspergillus spp. Blastomycis dermatitidis. Candida spp. Coccidioides inimitis. Cryptococcus spp. ...

Medical Mycology

Title: Beveled Slide Style Author: Nan Shastry Last modified by: emad Created Date: 6/5/2006 7:52:32 PM Document presentation format: On-screen Show (4:3)

INTRODUCTION TO MYCOLOGY By Dr. Emad AbdElhameed Morad Lecturer of Medical Microbiology and Immunology Fungi are eukaryotic organisms. Their cell wall consists of chitin.

Title: MEDICINSKA MIKOLOGIJA u v o d Author: user Last modified by: Valentina Created Date: 11/19/2004 11:42:52 AM Document presentation format: On-screen Show (4:3)

superficial fungal infection dermatophytosis three genera known to cause disease-tricophyton - microsporum - epidermophyton tinea pedis chronic intertriginous type ...

A brief description about fungi

STEROID OLEH BURHANUDDIN TAEBE PENDAHULUAN Merupakan metabolit sekunder hewan / tumbuhan Asal usul biogenetik mengikuti pola reaksi pokok sama, menghasilkan kerangka ...

Phytophthora infestans. American Elms before and after. Dutch elm blight ... In 1940s, Marietta had approximately 2000 American elm trees. How many remain in 2003? ...

Title: PowerPoint Presentation Last modified by: c Created Date: 1/1/1601 12:00:00 AM Document presentation format: Ekran G sterisi Other titles

Recommended text books Basic and Clinical pharmacology, 10th or 11th edition, B.G.Katzung, LANGE medical book. Lippincott s ilustrated reviews: Pharmacology ...

... use in antifungal agents such as amphotericin which ... skin may be treated with topical application of antifungal agents miconazole and ...

Superficial and Cutaneous Mycoses Eva L.Dizon,MD Superficial Mycoses Superficial Do not elicit immune response No discomfort Cosmetic problems Limited to stratum ...

(Use in alzheimer disease, glaucoma) ... Statins inhibit this enzyme, ... Clinical Enzymology Author: Haiza Last modified by:

Novel Antifungal Agents Dr. Khaled H. Abu-Elteen Dr. Mawieh A. Hamad Department of Biological Sciences Faculty of Science- Hashemite University * * * * * CYP2C19 ...

Introduction Medical Mycology Prof. Dr. Asem Shehabi Faculty of Medicine University of Jordan General Fungi-1 Fungi are eukaryotic microorganisms..

... of Histoplasma capsulatum will often increase in bird and bat droppings. Infection occurs when airborne spores enter a host organism's respiratory tract ...

Market 2001 Mech of Action: Potent inhibitor of the fungal enzyme 1,3-(beta)-D glucan synthase. This enzyme catalyzes glucan polymerization ...

Anti-fungal agents Amphotericin B : It is active against wide range : Aspergillosis, Candida albicans, Cryptococcus neoformans, Coccidioides immitis, ...

Chemotherapeutic Agents Antibiotics Synthetic Drugs

MEDICAL MYCOLOGY. Arthur F. Di Salvo, MD. Reno, Nevada. Medical Mycology Outline. HOUR SUBJECT ... To impart sufficient basic science of the medically important ...

Candidiasis - an infection caused by a Candida spp. Candida is a yeast and is is part of the normal flora ... in opportunistic mycoses (following Candida spp) ...

Protein Evolution, Coevolution and Interaction Networks Day 3

Medical Mycology

... Aspergilus spp Hongos filamentosos Blastomyces dermatitidis Histoplasma capsulatum Coccidioides immitis NO TIENE ACTIVIDAD FRENTE A CRIPTOCOCO ESPECTRO ...

More recently, compounds have been altered. Features of antimicrobials ... Neomycin can't be taken internally. Tetracyclines can discolor teeth in children ...

Medical Mycology

Kingdom Fungi. Eukaryocytes. Ascomycota. Basidiomycota. Zygomycota. Mitosporic Fungi ... KINGDOM. CHARACTERISTIC. EXAMPLE. Monera. Prokaryocyte. Bacteria ...