Nateglinide PowerPoint PPT Presentations

Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research Rury R. Holman, MB, ChB, FRCP Professor of Diabetic Medicine Director, Diabetes Trials Unit ...

Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research` Rury R. Holman, MB, ChB, FRCP Professor of Diabetic Medicine Director, Diabetes Trials Unit ...

The ppt gives an insight into the Glinides group of medicines for treatment of Diabetes. It provides information about the working of Glinides as to how these are glucose lowering medicines and that they act by releasing insulin. It provides information about three medicines under the Glinide group – Repaglinide, Nateglinide and Mitiglinide. Repaglinide and Nateglinide can be added as second medicine to Metformin for treatment of diabetes. Along with diet and exercise, these medicines can help lower blood sugar effectively.

¢ Drug interactions of Meglitinides (Repaglinide & Nateglinide) are dealt in this presentation. ¢ Repaglinide is metabolized by the CYP3A4 and CYP2C8 and hence it interacts with Gemfibrozil, Azole antifungals, Dabrafenib, Montelukast, Macrolide antibiotics and Rifampicin. ¢ Nateglinide is metabolized by CYP2C9 (70%) and CYP3A4 (30%) and it interacts with Amiodarone and Macrolide antibiotics. It also interacts with NSAIDs, MAOIs, Trandolapril, Non selective beta blockers Thiazide diuretics, Corticosteroids, Danazol, Sympathomimetics, Phenytoin and St.John’s wort.

Primary end points: CV events, new-onset diabetes. NAVIGATOR ... Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research *Insulin secretagogue ...

DRUGS FOR THE TREATMENT OF DIABETES MELLITUS * * MEGLITINIDES e.g. Repaglinide, Nateglinide PHARMACOKINETICS Taken orally Rapidly absorbed ( Peak approx. 1hr ...

Essentials of diabetic care By Prof. Fathi El-Gamal Aminoacid derivative D-phenyl alanine ; eg. Nateglinide Drug combinations Any groups of drugs listed above can be ...

Les antidiab tiques oraux Les anciennes et les nouvelles mol cules et strat gies envisageables Pr Serge HALIMI

OVERVIEW OF DIABETES MELLITUS (TYPE 2) Bhushan Ghoorbin

management of diabetes mellitus

Title: Progress o da Diabetes Tipo II Author: Maputo Last modified by: Henrique Mendes Cabral Created Date: 2/24/2003 12:55:22 PM Document presentation format

Prevention Of Diabetes A Dream Or A Reality By Professor Dr Intekhab Alam Department of Medicine Postgraduate Medical Institute, Lady Reading Hospital ...

... Action of Currently Available Therapeutic Options Combination Antihyperglycemic Therapy Timeline for Therapy in Type 2 Diabetes Individualized Treatment ...

antidiabetic agents ji sl va

Learn the horrible effects your diabetes medicine have on your health and also know the secret to avoid the medicines and take controll of your life.

Diabetes Mellitus Overview and Treatments Andrew P. Vogt Chemistry 6116 Diabetes Mellitus : a group of diseases characterized by high levels of blood glucose ...

Initiating Insulin Therapy in Type 2 Diabetes DIABETES CARE, Feb. 2005 Raskin Philip for the INITIATE study group The INITIATE study: NovoMix 30 (BID) vs glargine ...

Gangrene. Amputation. Foot ulceration risk factors. History of previous ulceration ... Moisturise dry skin. No self-treating. Avoid direct heat. Suitable footwear ...

Title: PowerPoint Presentation Author: Al Humayyd Last modified by: xp Created Date: 1/19/2003 5:37:34 PM Document presentation format: (3 ...

Oral Treatments for Type 2 Diabetes Prescribing Support Pharmacist Glucose Homeostasis Glucose Homeostasis See NHSGGC guidelines on monitoring of blood glucose for ...

Title: Coaated stents: a new era Subject: theheart.org show Author: Conceptis Technologies Last modified by: sys admin Created Date: 2/9/2001 4:03:24 PM

Medication Presentation Torry A. Hansen Glyburide Generic name: Glyburide Brand name: Micronase Other brand names: DiaBeta, Glynase Classifications: Therapeutic ...

Drug interactions of Incretin mimetics (Exenatide) with other drugs like Warfarin, Digoxin, Paracetamol, Antibacterials, Thyroid hormones, Danazol and ACE inhibitors are dealt in this presentation. The interactions of Amylin analogue (Pramlintide) with other drugs such as Alpha glucosidase inhibitors, Danazol, ACE inhibitors, Thyroid hormones, Paracetamol and Antimuscarinics are also dealt in this presentation.

Farmaci del sistema endocrino e metabolico Farmacologia speciale DIABETE Diabete mellito Complicanze associate al diabete mellito TIPI DI INSULINA AD AZIONE RAPIDA AD ...

TERAPIA FARMACOLOGICA DEL DIABETE DI TIPO 2 Enrica Manicardi. Reggio Emilia, Oratorio Don Bosco, 16 settembre 2005 DM2 E UNA MALATTIA COMUNE, COMPLESSA CHE ...

ESTRATEGIAS PARA LA ATENCION OPTIMA. DEL PACIENTE CON DIABETES MELLITUS ... Drugs 54:355-368,1997, Dunn CJ, Faulds D. Drugs 60:607-615,2000. Insulino secretores ...

Sulfonylureas : stimulate cells to produce more insulin. 1st generation (1)Orinase (tolbutamide) (3)Tolinase (tolazamide) (6)Diabinese (chlorpropamide)

Diabetic patients take Insulin and/or other oral hypoglycemic and antihyperglycemic drugs to control their blood sugar levels. Along with antidiabetic medicines they may take drugs such as OTC medicines, prescription medicines, etc.to treat other illnesses which may interact with them. Drug interactions of Insulin with other drugs like Fluoroquinolones, Betablockers, Aspirin, Thiazolidinediones, Antipsychotics, Androgens, Antimalarials and Orlistat are dealt in this presentation. The interactions of Insulin with Complementary and alternative medicines (CAM) such as Bitter melon, Ginkgo, Ginseng, Gymnema, Licorice and Fenugreek with smoking and with alcohol are also dealt in this presentation.

Clinical Case 9 G. V., a 42-year-old male showbiz personality was known to have Juvenile-onset diabetes. For one week, he complains of feeling bloated or full ...

SGLT2 is the main site of filtered glucose reabsorption; reduction of filtered glucose reabsorption and lowering of RTG result in increased urinary excretion of ...

THE DIABETIC TRIAD. Think of diabetes as a three legged ... DIABETIC DIET. Timing of Meals. Content of Meal. Protein 10-20% Carbohydrates and MonoFats 60-70 ...

Diabetes Mellitus Fifth Stage-Medicine Dr. Sarbast Fakhradin MBChB, MSc Diabetes Care & Management * * * * * * Comprehensive diabetes care of type 2 DM Patient ...

. Management of Type 2 Diabetes Mellitus: A New Paradigm ...

IMPLICATIONS OF UKPDS GSK Advisory Board 24 May 2003 Dr. J. R. Conway Worldwide rates of diabetes mellitus: predictions 2.2 Million Canadians Have Diabetes Mellitus ...

Frequency of diagnosed and undiagnosed diabetes and IGT, by age (U.S. data - Harris) ... lipolysis. release of NEFA. hepatic glucose production ...

... disease begins with development of key metabolic abnormality, insulin resistance. ... Metabolic abnormality that triggers the onset of type 2 DM ...

Symptoms of Type 1 Diabetes. Cardinal symptoms. Polydipsa (increased thirst) ... Symptoms of Type 2 Diabetes. Cardinal symptoms are uncommon. Weight gain (or loss) ...

Practical Considerations in Clinical Management

Elevated triglycerides and LDL; reduced HDL; High blood pressure; obesity; ... Phenformin induces lactic acidosis .... Fatal in 3 ...

Title: Diabetes Mellitus Author: hho Last modified by: Jennifer Shieck Created Date: 2/18/2004 7:49:49 PM Document presentation format: On-screen Show

Pharmacotherapy of Diabetes Mellitis

DIABETES WORKSHOP IN GENERAL PRACTICE Dr John Rochford GP Sharnbrook

TYPE 2 DIABETES MELLITUS Richard Sachson MD DIABETES AND GESTATIONAL DIABETES AMONG ADULTS IN THE U.S. -2001 Diabetes and Obesity: The Continuing Epidemic ...

Title: Nursing Board Review Author: morpheus Last modified by: Myk Created Date: 10/19/2004 2:47:18 AM Document presentation format: On-screen Show

... Usually lean and young patients but this trend in changing Non-Insulin-Dependent Diabetes Mellitus ... in Type I and Type II diabetics as an add ...

Some medicines help insulin release from the pancreas ... 2 hour post-prandial 140mg/dl. Bedtime. 100-140mg/dl. A1c 6.5% ADA Standards of Care ...

Title: Acute Renal Failure Author: Johns hopkins Last modified by: Jessica Joseph Created Date: 7/30/2002 12:40:54 AM Document presentation format

R duire les dommages de l'hyperglyc mie. R duire les autres facteurs ... ANTAGONISTES DES RECEPTEURS CB1. Rimonabant. Effets centraux. Effets p riph riques. Prise ...

Drug Safety in Chronic Kidney Disease Primary Care Clinician Conference 4/26/14 Michael J Choi, MD Johns Hopkins University School of Medicine mchoi3@jhmi.edu

Review medical therapies for type 2 DM. List important considerations in ... Slow absorption of carbohydrates and reduces rise in postprandial glucose levels ...

Based on 2 open-label trials, ... In other words, what percent of new users of each class (reading down), ... Probably closest to capturing true new diabetics ...

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Endocrinologist, Hamilton General Hospital www.drharper.ca Diabetes Mellitus Type 1, IDDM, Juvenile-onset Type 2, NIDDM, ... antibodies attack islets!

Update in Diabetes Management Oral Therapies. Amy M. Lugo, PharmD, BCPS, CDM ... Use in premenopausal anovulatory women may cause resumption of ovulation ...

Diarrhea and abdominal discomfort. Lactic acidosis if improperly prescribed ... Diet, exercise, Smoking, alcohol. BP. Weight. Macrovascular- CVA, IHD ...