Presentazione di PowerPoint

1
The Mediterranean School of Oncology
43th course
Highlights in the management of colorectal
cancer Rome, 1-2 February 2007
2
The Mediterranean School of Oncology An
educational program of
Consorzio Interuniversitario Nazionale per la
Bio-Oncologia
3
A Consortium among 14 Italian Universities
Ancona
Messina
Bologna
Napoli Federico II
Catanzaro
Palermo
Chieti-Pescara
Perugia
Ferrara
Roma La Sapienza
Foggia
Teramo
LAquila
4

• CARCINOMA DEL COLON-RETTO
• SCENARIO GLOBALE
• 2a causa di morte per cancro nei paesi
  occidentali!
• 1,000,000 nuovi casi 500,000 decessi/anno
• Alla diagnosi
• 70-80 malattia localizata, resecabile
• 50 stadio II
• 35 stadio III
• 40 (400,000/anno) ripresa di malattia dopo
• chirurgia potenzialmente curativa

5
Anni 90 ottimizzazione del 5-FU
Levamisole
LD leucovorin
5-FU
HD leucovorin
Bolus
Infusione continua
6
Sopravvivenza mediana CRC metastatico, Ia linea
Best supportive care
46 months
0
6
12
18
24
Median overall survival (months)
7
Nel 2007, cosa si può attendere un paziente
affetto da carcinoma metastatico del
colon-retto?
Risposte oggettive 50-70
Tempo alla progressione 8-11 mesi
Soparvvivenza globale 24-26 mesi
8
Oltre la I linea
Ia linea FOLFOX Bevacizumab
Va linea FOLFOX Cetuximab
IIa linea Irinotecan 5-FU (Bevacizumab)
VIa linea FOLFOX Cetuximab Bevacizumab
IIIa linea Cetuximab Irinotecan
VIIa linea XX YY
IVa linea Cetuximab Bevacizumab
Irinotecan
. .
9
Come identificare i pazienti R e NR alla terapia?
10
CRC Criteri di selezione usuali
100
100 pazienti trattati con CT dopo 5 anni
70 sono viventi anche senza CT (o-treated)
75
20 sono deceduti nonostante la CT
50
Usando il profilo despressione genica
Only 22.5 of pts will be overtreated
25
0
11
Patient goes to
Familiy doctor/health center
Population-based screening
Investigations diagnostic testing
Cancer diagnosed
Cancer not diagnosed
Treatment
Palliative care
Continuing treatment
Follow-up
Relapse
Terminal care
Cure
Long-term survival
Bereavement
12
Two classes 1. Foreign students (in
English) 2. Italian residents
All courses are accredited for CME by Ministero
della Salute, Italy or/and ESMO
13
10
600
Courses/year
8
Students/year
500
6
400
4
300
By December 2006 42 courses gt2200
students
2
200
0
0
2000
2002
2003
2004
2001
2005
2006
14
Scholarships

• Available to candidates lt30 years of age.
• To apply for a scholarship
• a brief curriculum vitae
• a letter of presentation from an authorised
• officer at the institute of affiliation. 

For information www. unich.it/mso.cinbo
15
MSO - 2007 Course
Calendar 1-2 February Highlights in the
management of colorectal cancer (E) 16-17
February Tumori del rene e melanoma progressi
della ricerca traslazionale e clinica
19-20 March Cardiotossicità da farmaci
antitumorali basi genetiche, diagnosi,
prevenzione e terapia 18-19 April Highlights
in the management of breast cancer (E) 25-26 May
Presente e futuro della terapia del dolore
neuropatico in oncologia 8-9 June
Personalized diagnostic and therapeutic
strategies in oncology (E) 20-21 July
Sessualità e cancro 5-6 October   
I tumori dellovaio 26-27 October
New oncology drugs pipeline update from bench
to bedside (E) 23-24 November
Controversie in oncologia (E) Courses in
English
16
The Formazione a Distanza in Oncologia (FADO)
Program
A MSO/CINBOs pilot project
Consorzio Interuniversitario Nazionale per la
Bio-Oncologia
17
FADO Program
Designed to build or enhance professional
knowledge, skills, and leadership in oncology
and related disciplines through distance/online
education training.
Teaching is made via satellite technology.
18
Target audience
1. Residents in medical oncology
2. Ph.D. students (Dottorato di Ricerca) in
oncology and related disciplines
Consorzio Interuniversitario Nazionale per la
Bio-Oncologia
19
FADO - Partners
Organization management
Technologies services
20
The Mediterranean Task Force for Cancer Control
(MTCC)
A MSO/CINBOs pilot project
Consorzio Interuniversitario Nazionale per la
Bio-Oncologia
21
MTCC
An innovative project to raise awareness about
cancer prevention and early detection via
satellite technology

• courses in modular print format
• videoconferences
• lectures-seminars-lessons

To provide a forum for distance learning
discussion among CINBO member Universities and
selected medical Institutions within the
mediterranean area
22
1st Meeting of the Mediterranean Task Force for
Cancer Prevention and Early Detection
October 4th, 2005
Taormina, Italy
With the participation of delegates from
Algeria
Croatia
Egypt
France
Greece
Albania
Jordan
Lebanon
Italy
Lybia
Morocco
Palestine
Portugal
Syria
Slovenia
Spain
Tunisia
Turkey