Nessun titolo diapositiva

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Bioinformatics Science that derives information
from computer analysis of biological data
Bioinformatics refers to the creation and
advancement of algorithms, computational and
statistical techniques, and theory to solve
formal and practical problems posed by or
inspired from the management and analysis of
biological data. Computational biology refers to
hypothesis-driven investigation of a specific
biological problem using computers, carried out
with experimental and simulated data, with the
primary goal of discovery and the advancement of
biological knowledge
Data
1) Information from genomes / genetic code
2) Biochemical results, patient statistics, etc.
3) Scientific literature
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Diego Sánchez Instituto de Biologia y Genética
Molecular Universidad de Valladolid-CSIC C/Sanz y
Forés s/n 47003 Valladolid Tfno 983-184814 Fax
983-184800 E-mail lazarill_at_ibgm.uva.es
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Databases (raw and curated-annotated data)
Sequence and structure databases (DNA and
proteins)
General DB GenBank, Protein structure (PDB),
SwissProt, ESTdb, SNPs
Genome DB Human Genome Mouse
Organism-specific Flybase ACEDB Zebrafish
Relational DB HomoloGene CDD Prosite...
Scientific literature Pubmed, Medline
Zoology Taxonomy, Tree of life
Global and relational DB Entrez Ensembl
GOdb
Web-based analysis platforms
NCBI ExPASy EBI
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Genes-proteins relationships Orthology,
homology, paralogy, analogy and xenology