Presentazione di PowerPoint

1
Detection of cytoskeleton depolymerization in a
single cell

• C. De Luca(a,b), A. Morales(a), G. Volpe(a), I.
  M. Geli(c), A. Sasso(b) and D. Petrov(a,d)
• ICFO - The Institute of Photonic Sciences -
  Barcelona, Spain
• Dipartimento di Scienze Fisiche, Università degli
  Studi di Napoli Federico II - Napoli, Italy
• IBMB - Institute of Molecular Biology of
  Barcelona - Bercelona, Spain
• ICREA - Catalan Institute of Advanced Research
  and Studies - Barcelona, Spain

Frequency corner measurements
Conclusions References
We demonstrate that the tracking of Brownian
motion of a trapped living cell can be used as a
sensitive indicator of cellular state. It is an
inherent cell marker that offers an alternative
to traditional techniques and opens the door to
new systems for cell identification and sorting,
especially in integrated devices (Lab on a
Chip). 1 G. Volpe, G. P. Singh, and D. Petrov,
Dynamics of a Growing Cell in an Optical Trap,
Appl. Phys. Lett. 88, 231106 (2006) 2 M.-T.
Wei, K. Yang, A. Karmenyan, and A. Chiou,
Three-dimensional optical force field on a Chnese
hamster ovary cell in a fiber-optical dual-beam
trap, Opt. Express 14, 3056 (2006) 3 N.
Malagnino, G. Pesce, A. Sasso and E. Arimondo
Measurements of trapping efficiency and
stiffness in Optical Tweezers Opt. Commun. 214,
15 (2002).