DEN 17'3'2005

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DEN17.3.2005

• Dr Jacqueline Mukoyogo

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Mr P H

• 26 year old
• PC
• Immunisation for Hepatitis B
• PMHx
• Acne vulgaris
• Appendisectomy
• SHx
• Fireman
• Smoker
• Rugby player

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Immunisation options
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Which option?Evidence?

• Study-Ann Clin Microbiol Antimicro.2003
• Comparison of accelerated and classic vaccination
  schedules against Hepatitis B3 week Hepatitis B
  vaccination schedule provides immediate and
  protective immunity
• 120 subjects-2 goups-vaccinated(0,1,2 m),
  accelerated(0, 10 21 days)
• 3 week vaccination provided protection within
  shorter time compared to classic schedule showing
  that in order to provide rapid antibody
  production against hepatitis B virus accelerated
  vaccination schedule seems to be good preference

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Comparison of Anti HBs(aHBs) responses after
accelerated(A) and traditional(B) vaccination